Age verification
GHK-Cu supplied as a lyophilised 50 mg vial. Tested at 99.513% purity by an independent laboratory. Certificate published under lot #109384.
98+
Every lot has a certificate from an independent laboratory, typically for HPLC purity and identity.
1–3
Orders are usually prepared for shipment within 1–3 business days, then tracked end to end.
COA
Read the latest certificate for the compound before you place the order, not after.
Certificate of analysis
The certificate of analysis an independent laboratory issued for the lot listed here: typically purity by HPLC and identity, and endotoxins where the laboratory tested them.
Lyophilised powder is stable at ambient temperature in transit. On arrival, keep sealed vials refrigerated at 2–8 °C, dry and dark. For storage beyond three months, keep at −20 °C.
Follow your laboratory's own protocol.
Refrigerate at 2–8 °C and protect from light. Use within 30 days. Discard if the solution becomes cloudy or discoloured.
For laboratory research use only. Not for human or veterinary consumption. Not a drug or dietary supplement.
Research record
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding tripeptide complex widely studied in cellular and molecular research. Researchers investigate GHK-Cu for its involvement in copper-associated signaling pathways, gene-expression regulation, extracellular matrix biology, and cellular communication processes. Sold for research use only.
01
GHK is a naturally occurring tripeptide found in human serum, reported at around 200 ng/ml at age 20 and around 80 ng/ml by age 60. It has high affinity for copper and forms the GHK-Cu chelate; both the peptide and the chelate are described as having tissue-remodelling and anti-inflammatory properties in vitro and in vivo.
02
A review of newer genetic data proposes that the breadth of reported actions reflects multiple biochemical pathways under the tripeptide's regulation, and catalogues reported effects on collagen, elastin and glycosaminoglycan synthesis, blood vessel and nerve outgrowth, and suppression of molecules associated with ageing.
03
More recent work identifies specific targets rather than broad activity: rescue of cigarette-smoke-induced skeletal muscle dysfunction through a sirtuin 1-dependent pathway, and attenuation of lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6.
| Research area | Assay |
|---|---|
| Copper coordination | Chelate formation and stability of the Cu(II) complex |
| Matrix synthesis | Collagen, elastin and glycosaminoglycan readouts in fibroblast culture |
| Pathway targeting | SIRT1-dependent readouts in skeletal muscle models |
| Redox and fibrosis | Peroxiredoxin 6 targeting in lung inflammation models |
| Inflammation models | CuSO4- and LPS-induced inflammation in zebrafish larvae |
A 2024 review notes that published information on the skin permeability, effectiveness and physicochemical properties of GHK remains insufficient. The record is preclinical and in vitro, and the compound holds no FDA approval.
Regulatory status as of October 2026.
2D structure · PubChem CID 71587328
Ordering, handling and compliance. Anything not covered here, write to support@pureforgelabs.com.
Every compound we sell is supplied for laboratory research and development only. It is not a drug, not a supplement, and not intended to diagnose, treat, cure or prevent any condition in humans or animals. Buying from this site means you are acquiring it for in vitro or other controlled research work.
Purchasers must be 21 or older and are responsible for compliance with the law where they take delivery. We ship to research institutions, laboratories and qualified individual researchers in the United States only. We do not ship to jurisdictions where these compounds are restricted.
Check three things in order. First, the lot code on the certificate matches the lot listed on the product page and in your order. Second, where the report gives an HPLC purity, its chromatogram shows a single dominant peak at the stated figure; a blend's report shows a peak for each compound. Third, where the lab ran mass spectrometry, the measured mass matches the expected molecular weight of the compound. Anything that does not line up, send us the lot code.
Unopened vials keep at ambient temperature short term, as in transit; on arrival, refrigerate them at 2–8 °C, and keep them at −20 °C beyond three months. Reconstitute following your laboratory's own protocol; once in solution, refrigerate at 2–8 °C, protect from light and use within 30 days.
Orders are normally prepared for shipment within 1–3 business days and ship to street addresses in the United States only — not to P.O. boxes or APO/FPO/DPO military addresses. Shipping is free on orders over $150 and a flat $14.95 below that.
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Keep the vial and all the packaging, photograph the damage and email support@pureforgelabs.com within 48 hours of delivery with your order number. Once the claim is verified, we replace the vial or refund what you paid for it. Please do not send anything back unless we ask you to — apart from damaged or incorrect items, all sales are final.
Yes, by quote. The volume tiers on the product pages go up to five vials; for larger research quantities email support@pureforgelabs.com with the compounds and amounts, and we will quote per gram.
FOR RESEARCH USE ONLY. NOT FOR HUMAN OR VETERINARY CONSUMPTION. This product is intended solely for legitimate laboratory, analytical, and scientific research. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease and is not intended for human or veterinary administration or consumption. All products are intended for research and identification purposes only. These products are not intended for human dosing, injection, or ingestion.
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Damaged in transit, or not the product on your order? Email support@pureforgelabs.com within 48 hours of delivery with photos of the item and the package — once verified, we replace it or refund it. All other sales are final.
All compounds are sold for in-vitro laboratory research only. Not for human or veterinary use, not a drug or dietary supplement. By placing this order you confirm you are a qualified researcher aged 21 or over and that the material will not be administered to humans or animals.