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Peptides 99.87% purity Research Use Only · Not for Human or Veterinary Consumption

BPC-157

BPC-157 supplied as a lyophilised 5 mg vial. Tested at 99.87% purity by an independent laboratory. Certificate published under lot 7291048563.

Purity
99.87% HPLC
Mol. weight
1419.53 g/mol
Sequence
GEPPPGKPADDAGLV
Current lot
7291048563 COA →
$42.99 $29.99 per vial, 5 mg

Vial size

Quantity — volume pricing

+$9.99
In stock · ships today Lot 7291048563 View COA →

99+

Third-party purity

Every lot goes to an independent laboratory for HPLC purity and LC-MS identity before release.

24h

Same-day dispatch

Orders placed before 2 PM Pacific leave the warehouse the same working day, tracked end to end.

COA

Published before purchase

Read the certificate for the exact lot you will receive before you place the order, not after.

Certificate of analysis

Every vial ships against its own lot

The certificate here belongs to the vial you are ordering, not to a representative batch. Purity by HPLC, identity by LC-MS and endotoxin screening, run by an independent laboratory.

Lot 7291048563
Purity 99.87% HPLC
Identity Confirmed by HPLC-MS
Endotoxin < 0.079 EU/mL
Laboratory MZ Biolabs
Tested December 29, 2025
coa scan

Specification

Purity
99.87% by HPLC
Sequence
GEPPPGKPADDAGLV
CAS number
137525-51-0
Molecular weight
1419.53 g/mol
Molecular formula
C62H98N16O22
Physical form
Lyophilised white powder
Net quantity
5 mg per vial
Current lot
7291048563
Tested by
MZ Biolabs
SKU
PFL-BPC-157-5-MG

Storage & reconstitution

Before opening

Lyophilised powder is stable at ambient temperature in transit. On arrival, store sealed vials in a cool, dry, dark place. For storage beyond three months, keep at −20 °C.

Reconstitution

Add bacteriostatic water slowly down the inner vial wall. Do not shake — swirl gently until fully dissolved.

After reconstitution

Refrigerate at 2–8 °C and protect from light. Use within 30 days. Discard if the solution becomes cloudy or discoloured.

For laboratory research use only. Not for human or veterinary consumption. Not a drug or dietary supplement.

Research record · preclinical

Three characterised lines of work

BPC-157 is a linear 15-residue peptide with five proline residues, three of them consecutive at positions 3 to 5. The constrained backbone is the structural basis for the stability in acidic media reported across the literature, and the reason the compound has been characterised across more experimental systems than most peptides of its length.

01

Nitric oxide signalling

In isolated rat aorta preparations the peptide produced concentration-dependent vasodilation that was endothelium-dependent and abolished by L-NAME. Co-immunoprecipitation traced the response to phosphorylation of Src, caveolin-1 and endothelial nitric oxide synthase, with reduced binding between caveolin-1 and eNOS.

02

Growth factor receptors

Microarray analysis of rat Achilles tendon fibroblasts identified the growth hormone receptor among the most abundantly up-regulated genes after exposure, confirmed at both mRNA and protein level, with downstream Janus kinase 2 activation on subsequent growth hormone stimulation.

03

Angiogenic signalling

Published reviews position the peptide alongside standard angiogenic growth factors and summarise the vascular observations recorded in tendon, ligament, muscle and bone models, with a dedicated review covering blood vessel formation specifically.

In vitro applications

Research area Assay
Nitric oxide signalling Src, caveolin-1 and eNOS phosphorylation in endothelial preparations
Receptor expression GH receptor and JAK2 pathway profiling in tendon fibroblast culture
Angiogenesis Endothelial tube formation and vascular marker expression
Cell migration Fibroblast outgrowth and migration in tissue-repair models
Peptide stability Analytical characterisation of proline-rich sequences under varied pH

A 2025 systematic review screened 544 articles published between 1993 and 2024 and included 36 studies, of which 35 were preclinical. The authors noted the compound holds no FDA approval and that the published record remains overwhelmingly preclinical.

Structure

BPC-157 2D structure

2D structure · PubChem CID 9941957

References

  1. 1 Hsieh MJ et al. (2020) Modulatory effects of BPC 157 on vasomotor tone. Scientific Reports. PMC7555539
  2. 2 Sikiric P et al. (2014) BPC 157–NO-system relation. Curr Pharm Des. 10.2174/13816128113190990411
  3. 3 Chang CH et al. (2014) GH receptor expression in tendon fibroblasts. Molecules. PMC6271067
  4. 4 Chang CH et al. (2011) Tendon outgrowth, survival and migration. J Appl Physiol. 10.1152/japplphysiol.00945.2010
  5. 5 Seiwerth S et al. (2018) BPC 157 and standard angiogenic growth factors. Curr Pharm Des. 10.2174/1381612824666180712110447
  6. 6 Seiwerth S et al. (2021) BPC 157 and wound healing. Front Pharmacol. 10.3389/fphar.2021.627533
  7. 7 Vasireddi N et al. (2025) Emerging use in orthopaedic sports medicine: a systematic review. HSS Journal. PMC12313605

Researcher notes

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Common questions

Ordering, handling and compliance. Anything not covered here, write to support@pureforgelabs.com.

What does research use only actually mean?

Every compound we sell is supplied for laboratory research and development only. It is not a drug, not a supplement, and not intended to diagnose, treat, cure or prevent any condition in humans or animals. Buying from this site means you are acquiring it for in vitro or other controlled research work.

Who is allowed to order?

Purchasers must be 21 or older and are responsible for compliance with the law where they take delivery. We ship to research institutions, laboratories and qualified individual researchers. We do not ship to jurisdictions where these compounds are restricted.

How do I read the certificate of analysis?

Check three things in order. First, the lot code on the certificate matches the code printed on your vial. Second, the HPLC chromatogram shows a single dominant peak with the stated purity figure. Third, the LC-MS mass matches the expected molecular weight, here 1419.56 g/mol. Anything that does not line up, send us the lot code.

How do I reconstitute and store it?

Add bacteriostatic water slowly down the inner wall of the vial and swirl — never shake. Once in solution, refrigerate at 2–8 °C, protect from light and use within 30 days. Unopened vials keep at ambient temperature short term, or at −20 °C beyond three months.

When does it ship and how?

Orders placed before 2 PM Pacific dispatch the same working day. Domestic delivery is two days, with tracking sent on dispatch. Shipping is free on orders over $200. International orders go out with a commercial invoice; transit is typically five to nine days.

What payment methods do you take?

Institutional purchase orders and bank transfer are available on wholesale accounts — apply through the wholesale programme and we will set up terms.

What if a vial arrives damaged?

Photograph the vial and outer packaging and email us within 48 hours of delivery. We replace damaged or compromised vials at our cost. Unopened vials can be returned within 30 days; opened vials cannot be resold and are not returnable.

Do you handle bulk and wholesale orders?

Yes. Volume pricing on this page runs to five vials; beyond that, a wholesale account gives tiered pricing, reserved lots and consolidated shipping. Reserved lots matter for multi-month studies where you need the same batch throughout.

FOR RESEARCH USE ONLY. NOT FOR HUMAN OR VETERINARY CONSUMPTION. This product is intended solely for legitimate laboratory, analytical, and scientific research. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease and is not intended for human or veterinary administration or consumption. All products are intended for research and identification purposes only. These products are not intended for human dosing, injection, or ingestion.

$29.99
BPC-157 · 5 mg · 1 vial

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