Age verification
PT-141 supplied as a lyophilised 10 mg vial. Tested at 99.78% purity by an independent laboratory. Certificate published under lot RP218-16Mar26-8.
98+
Every lot has a certificate from an independent laboratory, typically for HPLC purity and identity.
1–3
Orders are usually prepared for shipment within 1–3 business days, then tracked end to end.
COA
Read the latest certificate for the compound before you place the order, not after.
Certificate of analysis
The certificate of analysis an independent laboratory issued for the lot listed here: typically purity by HPLC and identity, and endotoxins where the laboratory tested them.
Lyophilised powder is stable at ambient temperature in transit. On arrival, keep sealed vials refrigerated at 2–8 °C, dry and dark. For storage beyond three months, keep at −20 °C.
Follow your laboratory's own protocol.
Refrigerate at 2–8 °C and protect from light. Use within 30 days. Discard if the solution becomes cloudy or discoloured.
For laboratory research use only. Not for human or veterinary consumption. Not a drug or dietary supplement.
Research record
PT-141 also known as Bremelanotide is a synthetic derivative of alpha-melanocyte-stimulating hormone. It has been studied for its interactions with melanocortin receptors particularly melanocortin-4 and melanocortin-1. Research has explored its potential role in influencing physiological processes such as sexual function and immune response as well as its broader effects within these pathways.
01
A synthetic analogue of the neuropeptide hormone alpha melanocyte-stimulating hormone, described as having high affinity for the melanocortin type 4 receptor, which is thought to be important for sexual function and gives the compound the potential to modulate brain pathways involved in sexual response. A 2023 review of the central melanocortin system places it alongside setmelanotide and afamelanotide as melanocortin-targeting peptides that reached approval.
02
The compound was first described in development as a candidate for erectile dysfunction and female sexual dysfunction, with a phase IIb trial in erectile dysfunction completed in 2003 and phase III planned for 2005. It was approved in 2019 for premenopausal women with acquired, generalised hypoactive sexual desire disorder.
03
A safety review covering the whole development programme, 3500 subjects across 43 completed studies with phase 3 exposure of up to 18 months, gives the most common adverse events against placebo as nausea at 40.0 against 1.3 percent, flushing at 20.3 against 1.3 percent and headache at 11.3 against 1.9 percent. Separately, a drug-induced liver injury monograph records mild serum enzyme elevations during therapy and rare instances of clinically apparent acute liver injury.
| Research area | Assay |
|---|---|
| Receptor binding | Melanocortin type 4 receptor affinity within the melanocortin family |
Bremelanotide holds an FDA approval, but a narrow one, and the rates in the third panel come from its development programme rather than from any other use: nausea was reported in 40 percent of treated participants against 1.3 percent on placebo. Reviews of the condition it was approved for describe its underlying physiology as still unknown.
Regulatory status as of October 2026.
2D structure · PubChem CID 9941379
Ordering, handling and compliance. Anything not covered here, write to support@pureforgelabs.com.
Every compound we sell is supplied for laboratory research and development only. It is not a drug, not a supplement, and not intended to diagnose, treat, cure or prevent any condition in humans or animals. Buying from this site means you are acquiring it for in vitro or other controlled research work.
Purchasers must be 21 or older and are responsible for compliance with the law where they take delivery. We ship to research institutions, laboratories and qualified individual researchers in the United States only. We do not ship to jurisdictions where these compounds are restricted.
Check three things in order. First, the lot code on the certificate matches the lot listed on the product page and in your order. Second, where the report gives an HPLC purity, its chromatogram shows a single dominant peak at the stated figure; a blend's report shows a peak for each compound. Third, where the lab ran mass spectrometry, the measured mass matches the expected molecular weight of the compound. Anything that does not line up, send us the lot code.
Unopened vials keep at ambient temperature short term, as in transit; on arrival, refrigerate them at 2–8 °C, and keep them at −20 °C beyond three months. Reconstitute following your laboratory's own protocol; once in solution, refrigerate at 2–8 °C, protect from light and use within 30 days.
Orders are normally prepared for shipment within 1–3 business days and ship to street addresses in the United States only — not to P.O. boxes or APO/FPO/DPO military addresses. Shipping is free on orders over $150 and a flat $14.95 below that.
We take credit and debit cards, paid securely at checkout. Bank transfers and purchase orders are not available at the moment.
Keep the vial and all the packaging, photograph the damage and email support@pureforgelabs.com within 48 hours of delivery with your order number. Once the claim is verified, we replace the vial or refund what you paid for it. Please do not send anything back unless we ask you to — apart from damaged or incorrect items, all sales are final.
Yes, by quote. The volume tiers on the product pages go up to five vials; for larger research quantities email support@pureforgelabs.com with the compounds and amounts, and we will quote per gram.
FOR RESEARCH USE ONLY. NOT FOR HUMAN OR VETERINARY CONSUMPTION. This product is intended solely for legitimate laboratory, analytical, and scientific research. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease and is not intended for human or veterinary administration or consumption. All products are intended for research and identification purposes only. These products are not intended for human dosing, injection, or ingestion.
One short email when something changes. No drip campaigns.
Damaged in transit, or not the product on your order? Email support@pureforgelabs.com within 48 hours of delivery with photos of the item and the package — once verified, we replace it or refund it. All other sales are final.
All compounds are sold for in-vitro laboratory research only. Not for human or veterinary use, not a drug or dietary supplement. By placing this order you confirm you are a qualified researcher aged 21 or over and that the material will not be administered to humans or animals.