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L-Carnitine 600 mg/10 ml supplied as a solution. Tested at 99.9% purity by an independent laboratory. Certificate published under lot COA4772.
98+
Every lot has a certificate from an independent laboratory, typically for HPLC purity and identity.
1–3
Orders are usually prepared for shipment within 1–3 business days, then tracked end to end.
COA
Read the latest certificate for the compound before you place the order, not after.
Certificate of analysis
The certificate of analysis an independent laboratory issued for the lot listed here: typically purity by HPLC and identity, and endotoxins where the laboratory tested them.
Not needed — the vial is supplied as a ready solution.
Keep the vial sealed and away from heat and light until needed.
For laboratory research use only. Not for human or veterinary consumption. Not a drug or dietary supplement.
Research record
L-carnitine is an amino-acid derivative needed to carry long-chain fatty acids across the inner mitochondrial membrane for β-oxidation. The body makes it from lysine and methionine and takes it in from food, mainly meat and dairy products, and cells accumulate it through the high-affinity transporter OCTN2.
01
Carnitine shuttles long-chain fatty acyl groups into the mitochondrial matrix and, by forming acylcarnitines, protects the cell from accumulating acyl-CoA. Skeletal muscle holds large amounts but cannot make it, and depends on uptake from the blood.
02
Defects in the OCTN2 transporter cause primary carnitine deficiency, with low serum carnitine and urinary losses; it can present early with hypoketotic hypoglycaemia and hepatic encephalopathy, or later with skeletal and cardiac myopathy. At high concentrations carnitine also enters cells through the amino-acid transporter B0,+. Secondary deficiencies follow disorders that increase carnitine excretion as acylcarnitines.
03
Because free carnitine appears to limit fatty acid oxidation as exercise intensity rises, supplementation has been proposed to improve performance; reviews find the question unresolved, with differences in intensity, training status, dose, route and timing behind conflicting results.
| Research area | Assay |
|---|---|
| Fatty acid oxidation | Mitochondrial β-oxidation flux |
| Transport | OCTN2-mediated uptake in cultured cells |
| Acylcarnitine profiling | Tandem mass spectrometry of acylcarnitines |
| Cardiac metabolism | Substrate use in heart models |
Levocarnitine is an approved medicine for carnitine deficiency; that approval applies to the licensed pharmaceutical product, not to research material such as this solution. Outside deficiency states, reviews describe the evidence for effects on performance and recovery as conflicting.
Regulatory status as of October 2026.
2D structure · PubChem CID 10917
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