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Peptide Blends Research Use Only · Not for Human or Veterinary Consumption

BPC-157 / TB-500 10/10 mg

BPC-157 / TB-500 10/10 mg supplied as a lyophilised vial. Certificate published under lot #148941.

Current lot
#148941 COA →
$144.99 $99.99 per vial, 10/10 mg

Quantity — volume pricing

30 ml +$14.99
In stock Lot #148941 View COA → $50 minimum order

At a glance

1–3

Business days to dispatch

Orders are usually prepared for shipment within 1–3 business days, then tracked end to end.

COA

Published before purchase

Read the latest certificate for the compound before you place the order, not after.

Certificate of analysis

The laboratory's report for the current lot

The certificate of analysis an independent laboratory issued for the lot listed here: typically purity by HPLC and identity, and endotoxins where the laboratory tested them.

Lot #148941
Identity Confirmed by HPLC · BPC-157 12.58 mg + TB-500 12.10 mg per vial (purity not measured)
Laboratory Janoshik
Tested April 21, 2026

Specification

Physical form
Lyophilised white powder
Net quantity
10/10 mg per vial
Current lot
#148941
Tested by
Janoshik
SKU
PFL-BPC-157-TB-500-10-10-MG

Storage & reconstitution

Before opening

Lyophilised powder is stable at ambient temperature in transit. On arrival, keep sealed vials refrigerated at 2–8 °C, dry and dark. For storage beyond three months, keep at −20 °C.

Reconstitution

Follow your laboratory's own protocol.

After reconstitution

Refrigerate at 2–8 °C and protect from light. Use within 30 days. Discard if the solution becomes cloudy or discoloured.

For laboratory research use only. Not for human or veterinary consumption. Not a drug or dietary supplement.

Research record

Three characterised lines of work

A two-component research vial: BPC-157 and TB-500, 10 mg each in one lyophilised powder. BPC-157 is a 15-residue, proline-rich peptide; TB-500 is a peptide derived from thymosin β4, the actin-binding protein most of its literature concerns.

01

BPC-157 component

In isolated rat aorta preparations the pentadecapeptide produced concentration-dependent vasodilation that was endothelium-dependent and abolished by L-NAME, with co-immunoprecipitation tracing the response to phosphorylation of Src, caveolin-1 and endothelial nitric oxide synthase. Separately, microarray analysis of rat Achilles tendon fibroblasts identified the growth hormone receptor among the genes whose expression rose most after exposure, confirmed at both mRNA and protein level.

02

Thymosin component

TB-500 derives from thymosin beta 4, whose identified molecular function is sequestration of monomeric G-actin, with a dissociation constant in the micromolar range that allows fast binding and release, and beta-thymosins are described as the main intracellular G-actin-sequestering peptides in most cells. This is the one activity in the pair with an explanation grounded in a defined molecular interaction.

03

Two routes in one vial

Orthopaedic reviews catalogue the two peptides together as wound-healing agents, but the mechanisms described for them do not overlap: one is discussed in terms of nitric oxide and angiogenic signalling, the other in terms of actin monomer binding and the cytoskeleton. Those reviews place the compounds side by side rather than reporting a result from the mixture, so the pairing rests on the two acting through separate routes rather than on a measured combined effect.

Published research areas

Research area Assay
Nitric oxide signalling Src, caveolin-1 and eNOS phosphorylation in endothelial preparations
Receptor expression Growth hormone receptor and JAK2 profiling in tendon fibroblast culture
Actin dynamics G-actin binding and sequestration assays
Angiogenesis Vessel formation in preclinical tissue and cardiac models
Cell migration Fibroblast outgrowth and motility readouts in tissue-repair models

Everything above was established on the two peptides separately. No controlled study of this mixture was found: the reviews that name both list them alongside one another rather than reporting an outcome from the combination, so any interaction between them is an assumption here and not a finding. A 2025 systematic review of BPC-157 screened 544 articles published between 1993 and 2024 and included 36 studies, of which 35 were preclinical. Reviews of thymosin beta 4 note variable effect sizes across animal models and call for pharmacokinetic work before clinical development. Neither compound holds FDA approval.

Regulatory status as of October 2026.

References

  1. 1 Hsieh MJ et al. (2020) Modulatory effects of BPC 157 on vasomotor tone. Scientific Reports. PMC7555539
  2. 2 Chang CH et al. (2014) GH receptor expression in tendon fibroblasts. Molecules. PMC6271067
  3. 3 Hannappel E (2007) beta-Thymosins. Ann N Y Acad Sci. 10.1196/annals.1415.018
  4. 4 Bubb MR (2003) Thymosin beta 4 interactions. Vitam Horm. 10.1016/s0083-6729(03)01008-2
  5. 5 Goldstein AL et al. (2012) Thymosin beta 4: a multi-functional regenerative peptide. Expert Opin Biol Ther. 10.1517/14712598.2012.634793
  6. 6 Rahman OF et al. (2026) Therapeutic peptides in orthopaedics: applications, challenges and future directions. J Am Acad Orthop Surg Glob Res Rev. 10.5435/JAAOSGlobal-D-25-00236
  7. 7 Mayfield CK et al. (2026) Injectable peptide therapy: a primer for orthopaedic and sports medicine physicians. Am J Sports Med. 10.1177/03635465251357593
  8. 8 Vasireddi N et al. (2025) Emerging use in orthopaedic sports medicine: a systematic review. HSS Journal. PMC12313605

Common questions

Ordering, handling and compliance. Anything not covered here, write to support@pureforgelabs.com.

What does research use only actually mean?

Every compound we sell is supplied for laboratory research and development only. It is not a drug, not a supplement, and not intended to diagnose, treat, cure or prevent any condition in humans or animals. Buying from this site means you are acquiring it for in vitro or other controlled research work.

Who is allowed to order?

Purchasers must be 21 or older and are responsible for compliance with the law where they take delivery. We ship to research institutions, laboratories and qualified individual researchers in the United States only. We do not ship to jurisdictions where these compounds are restricted.

How do I read the certificate of analysis?

Check three things in order. First, the lot code on the certificate matches the lot listed on the product page and in your order. Second, where the report gives an HPLC purity, its chromatogram shows a single dominant peak at the stated figure; a blend's report shows a peak for each compound. Third, where the lab ran mass spectrometry, the measured mass matches the expected molecular weight of the compound. Anything that does not line up, send us the lot code.

How should it be stored?

Unopened vials keep at ambient temperature short term, as in transit; on arrival, refrigerate them at 2–8 °C, and keep them at −20 °C beyond three months. Reconstitute following your laboratory's own protocol; once in solution, refrigerate at 2–8 °C, protect from light and use within 30 days.

When does it ship and how?

Orders are normally prepared for shipment within 1–3 business days and ship to street addresses in the United States only — not to P.O. boxes or APO/FPO/DPO military addresses. Shipping is free on orders over $150 and a flat $14.95 below that.

What payment methods do you take?

We take credit and debit cards, paid securely at checkout. Bank transfers and purchase orders are not available at the moment.

What if a vial arrives damaged?

Keep the vial and all the packaging, photograph the damage and email support@pureforgelabs.com within 48 hours of delivery with your order number. Once the claim is verified, we replace the vial or refund what you paid for it. Please do not send anything back unless we ask you to — apart from damaged or incorrect items, all sales are final.

Do you handle bulk and wholesale orders?

Yes, by quote. The volume tiers on the product pages go up to five vials; for larger research quantities email support@pureforgelabs.com with the compounds and amounts, and we will quote per gram.

FOR RESEARCH USE ONLY. NOT FOR HUMAN OR VETERINARY CONSUMPTION. This product is intended solely for legitimate laboratory, analytical, and scientific research. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease and is not intended for human or veterinary administration or consumption. All products are intended for research and identification purposes only. These products are not intended for human dosing, injection, or ingestion.

$99.99
BPC-157 / TB-500 10/10 mg · 10/10 mg · 1 vial

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